WASHINGTON: Astronomers studying stars and black holes have discovered that heavy metals emit low-energy electrons when exposed to X-rays at specific energies – a finding they say could lead to safer and more effective cancer treatments in the future.
The finding raises the possibility that implants made of gold or platinum can allow doctors to destroy tumours with low-energy electrons, while exposing healthy tissue to far less radiation than is possible today, the researchers said.
“As astronomers, we apply basic physics and chemistry to understand what’s happening in stars. We’re very excited to apply the same knowledge to potentially treat cancer,” study author Sultana Nahar of Ohio University was quoted as saying by LiveScience.
Computer simulations by the researchers suggested that hitting a single gold or platinum atom with a small dose of X-rays at a narrow range of frequencies produces a flood of more than 20 low-energy electrons.
So doctors can embed many heavymetal nanoparticles inside and around tumours, then hit them with a tailored shot of radiation, the researchers said
The resulting electron shower can obliterate a tumour and the process would greatly reduce a patient’s radiation exposure compared to most current radiation treatment methods.
For their research, presented at the International Symposium on Molecular Spectroscopy held recently in Columbus, the scientists built a prototype device that showed that specific X-ray frequencies can free low-energy electrons from heavy-metal nanoparticles. While the machine needs to be developed further, it’s providing a proof of principle for the potential cancer treatment technique, the astronomers said.
“This could lead to a combination of radiation therapy with chemotherapy using platinum as the active agent.”